PROTOCOL COMPARISON — MEDICATION ABORTION

FDA Approved Regimen (Based on evidence up to 1996)	Alternative Evidence-Based Regimen (Based on current evidence)
Oral Misoprostol	Buccal Misoprostol	Vaginal Misoprostol
Gestational age: Up to 49 days after first day of last period	Gestational age: Up to 63 days after first day of last period	Gestational age: Up to 63 days after first day of last period
Mifepristone 600 mg. (swallowed in the office)	Mifepristone 200 mg. (swallowed in the office)	Mifepristone 200 mg. (swallowed in the office)
Misoprostol 400 mcg. Oral use Swallowed in the office 48 hours after taking mifepristone	Misoprostol 800 mcg. Buccal use Used at home 24-48 hours after taking mifepristone Put in the cheek to melt	Misoprostol 800 mcg. Vaginal use Used at home 6-72 hours after taking mifepristone Put in the vagina
Office follow-up 10-15 days after taking mifepristone	Office follow-up 4-14 days after taking mifepristone	Office follow-up 4-14 days after taking mifepristone
3 office visits	2 office visits	2 office visits